The Jennifer Doudna
Framework
CRISPR Gene Editing & Scientific Courage
Jennifer Doudna co-discovered CRISPR-Cas9 and then, unusually for a scientist at her altitude, spent the following decade publicly wrestling with whether humanity should use it. Her framework is not just experimental rigour — it's the discipline of refusing to separate what can be done from what should be done. This framework captures Doudna's specific patterns: reading biology as an engineer reads a system, moving fast enough to win the priority race without sacrificing reproducibility, and the rare scientific virtue of pausing to ask whether the discovery serves the world.
- ✦Core philosophy — 2–3 sentences grounded in Jennifer Doudna's documented worldview
- ✦Five signature mental models — each named, with concrete examples from their work
- ✦Decision heuristics — the concrete rules they actually used
- ✦Signature questions — five questions that sound like Jennifer Doudna, not a generic MBA
- ✦What they would NOT do — the anti-patterns this framework rejects
- ✦Copy-paste activation prompt — drop straight into Claude or ChatGPT
- ✦Worked example — the framework applied to a realistic scenario
- →jennifer-doudna.zip — a native Claude Skill. Upload to Settings → Skills in Claude, or unzip to
~/.claude/skills/ - →jennifer-doudna-framework.md — plain markdown. Works in ChatGPT Custom GPTs, Gemini, Claude Projects, agent system prompts — anywhere
Save 25% with a bundle
Works as a Claude Skill (.zip) and as a plain .md for ChatGPT, Gemini & every LLM
Delivered to your email within 60 seconds · Secured by Stripe
Price includes UK VAT where applicable
Inspired by the documented thinking of Jennifer Doudna. A mental-model toolkit, not a literal representation. Delivered as a .md file compatible with Claude, ChatGPT, Gemini, and any LLM.